twokinds
Furry webcomic by Tom Fischbach, originally beginning in 2003 and still ongoing.
TwoKinds focuses on the tense relations between humankind and two races of anthropomorphic people - the Keidrans and the Basitins. The human protagonist, Trace Legacy, meets and falls in love with a keidran girl named Flora.
The comic was based on Tom's real life experiences with racial discrimination as a Korean-American, and has a central theme of acceptance of each other's differences.
This theme is reflected in the main cast, which consists of characters from various different backgrounds: the aforementioned Flora and Trace, a basitin named Keith Keiser tasked with tracking Trace down, and a wolf keidran named Natani struggling with his gender identity after a complicated mind meld with his older brother in order to save his life.